Totally Enclosed Downflow Booths are used when mills or other processing equipment cannot be contained within a normal Downflow Booth. An anti-chamber is provided to allow ingress and egress without allowing product migration out of the main work chamber. The anti-chamber is used for gowning apparel and PPE prior to entry into the main. It is also used for disposal of this equipment prior to exiting the area. In some applications, showers may be used as well.